This report describes the methodology and results of analyses performed to develop guidelines on (1) how to improve temporary traffic control at work zones in and near urban freeway interchanges, and (2) selecting appropriate pavement marking materials in work zones. Laboratory studies conducted using laptop computers and the Texas Transportation Institute (TTI) Driving Simulator indicate that continuing to use guide signs that no longer align directly over travel lanes (as often occurs during interchange reconstruction or widening) will degrade drivers’ abilities to properly choose lanes and negotiate through the interchange area. The use of temporary work zone diagrammatic signing and/or pavement marking symbols to denote route destinations for the various lanes will help offset this degradation. Other findings from the laboratory studies are discussed in the report. Monte Carlo simulation was used to model the interrelationships and variability of estimates of pavement marking material service life, project phase duration for which the marking is intended to provide service, and cost of the marking material in determining which pavement marking material would provide the lowest total expected cost for a particular work zone roadway condition. Matrices were generated of recommended pavement marking materials as a function of expected project phase duration and Annual Average Daily Traffic AADT. Additional matrices provided allow practitioners to adopt more liberal or conservative a ssumptions of the input variables when selecting a marking material.